Postdoctoral Fellows within GSK's Immunology Catalyst

Basic qualifications: 

The basic qualifications and any foundation experience required for this role are:

PhD degree or a M.D./PhD. in Immunology or related field (microbiology, genetics, biochemistry, medicine, etc.).

You must also have the ability to understand, interpret, and communicate complex scientific data; be comfortable conversing with opinion leaders regarding highly technical information; a self-starter able to handle multiple projects concurrently; possess a good balance of creative, analytical and strong communication skills; ability to be productive and successful in an intense work environment and a Team Player.

Preferred qualifications: 

In addition to the basic qualifications experience with cell and molecular biology, protein biochemistry, cell biology or flow cytometry is preferred.

Details: 

Please note this is a temporary role for up to 36 months.

Post-doctoral fellows within GSK’s Immunology Catalyst training programme will have the opportunity to:

• Be part of a unique network of immunologists working to discover the next breakthroughs in immunology. This network includes the group leaders in the Catalyst (high achieving academics on sabbatical at GSK), leading immunologists at GSK and world class immunologists on the external immunology board.
• Be part of cutting edge science to advance GSK’s mission ‘to improving the quality of human life by enabling people to do more, feel better, and live longer’.
• Accelerate your post-doctoral research with GSK’s extensive R&D engine.
• Bridge the gap from target identification to medicine for patients in-need by leveraging GSK’s: Tools, Technologies, Libraries, Samples, People, Knowledge Base, & Training program.

Postdoctoral research will be focused on addressing basic immunology questions and be under the supervision of academic experts who are members of the Immunology Catalyst. These mentors will be focused on providing a comprehensive training program and are expected to nurture skills that will enable postdocs to become independent scientific investigators. Catalyst members have been selected as cutting edge immunology experts and projects in this programme are optimal areas of science for post-doctoral training, as defined by the catalyst members and external immunology board members.

Your Postdoctoral experience will be accompanied by tremendous support at GSK with the opportunity for daily collaborations with world-class scientists.

You will be actively encouraged to publish and present your research at internal and external meetings and participate in the GSK R&D postdoc community, which will include scientific and social programming.

Ideal candidates will: Set direction & inspire, Work across boundaries, Release energy, Develop capabilities, Drive performance, and Live the GSK values, serving patients and consumers.

This PostDoctoral project with Seth Masters will be focused on new mechanisms that regulate the innate immune system. This will interrogate pathways that activate or inhibit cytosolic pattern recognition receptors that form inflammasome complexes. We will also research how this is controlled post-translationally, and perform limited small molecule screens as a way to investigate the function of these inflammatory pathways in myeloid cells. Studies may also look at epigenetic and metabolic changes related to the immune memory of myeloid cells in response to these inflammatory events. Approaches include the analsysis of cytokines, protein complexes, pathways of innate immune signalling and methods of genetic manipulation (CRISPR, lentivirus). We will employ these and other next generation techniques to make major advances in our understanding of the innate immune system.

This role will be located in Stevenage, UK working with Dr Seth Masters, who is on secondment from the Walter and Eliza Hall Institute, Melbourne, Australia. http://www.wehi.edu.au/people/seth-masters

Please use the cover letter to highlight how you fit the applicant profile and meet the skills and competencies for the role. Your cover letter along with your CV will be used to assess your application.

Closing date for applications: 28th October 2016

Thank you for your interest in this opportunity.

*LI-GSK

Contact information: 

You may apply for this position online by selecting the Apply now button.